资源利用和住院住院费用与多细胞血病患者的血栓栓塞事件相关
Jingbo Yu1, Julie Gayle2, Ning Rosenthal2
1Incyte Corporation, Health Economics and Outcomes, Wilmington, DE 19803, United States.
The oncologist
|March 4, 2025
概括
患有多细胞血病 (PV) 和血栓塞栓事件 (TE) 的患者需要承担大量的医疗费用,并面临高死亡率. 预防TEs对于管理PV和减少患者负担至关重要.
科学领域:
- 血液学 血液学 血液学
- 血管医学 血管医学
- 卫生经济学 卫生经济学
背景情况:
- 多细胞血病 (PV) 与医疗保健资源利用率 (HCRU) 和成本的增加有关.
- 患有PV的患者患有血栓栓塞事件 (TE) 的风险更高.
研究的目的:
- 描述PV和TE患者的HCRU,成本和死亡率.
- 分析来自美国的当代,现实世界的数据.
主要方法:
- 针对PV和TE的成年住院患者进行了回顾性队列研究.
- 来自623家美国医院的数据 (2017年1月至2020年6月) 通过PINCAI医疗保健数据库.
- 在指数TE相关住院后的2年随访.
主要成果:
- 分析了3494名患者;平均年龄为70.7岁,主要是男性和白人.
- 平均指数住院费用:24,403美元;损失:7天.
- 与TE相关的再接收率:6.4% (30天),20.0% (2年);所有原因死亡率:6.2% (指数),4.7% (2年随访).
结论:
- 住院HCRU,成本和死亡率对于TEs的PV患者来说是相当大的.
- 这些发现强调了在光伏管理中预防TE的必要性.
相关概念视频
Disorders of Erythrocytes
833
Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
833
Disorders of Hemostasis
676
Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
676
Anticoagulant Drugs: Low-Molecular-Weight Heparins
590
Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
590
Esophageal Varices-II: Clinical Features and Management
34
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
34
Vascular Resistance
3.2K
Vascular resistance is a critical concept in understanding blood flow dynamics in the circulatory system. It refers to the resistance that blood encounters as it flows through the blood vessels. This resistance is a key factor in determining blood pressure and cardiac workload.
The primary determinants of vascular resistance are vessel diameter, blood viscosity, and vessel length. Among these, vessel diameter plays the most significant role due to the fourth power relationship described by...
The primary determinants of vascular resistance are vessel diameter, blood viscosity, and vessel length. Among these, vessel diameter plays the most significant role due to the fourth power relationship described by...
3.2K


