评估适应比利时社区环境的D-PRESCRIBE干预措施可行性的协议 (END-IT CS研究)
Catherine Pétein1, Tina Chevallereau1, Josephine Aikpitanyi2
1Clinical Pharmacy and Pharmacoepidemiology research group, UCLouvain Louvain Drug Research Institute, Brussels, Belgium.
BMJ open
|March 4, 2025
概括
本研究评估了D-PRESCRIBE干预的可行性,这是一项由药剂师领导的计划,旨在减少老年人使用二二受体激动剂 (BZRA). 这项干预表明,在比利时社区环境中减轻BZRA的潜力.
科学领域:
- 老年人药理学 老年人药理学
- 实施科学 实施科学
- 社区药房实践 社区药房实践
背景情况:
- 在老年人中使用高二二胺受体激动剂 (BZRA) 需要进行抑郁治疗干预.
- 从加拿大改编的D-PRESCRIBE干预,在比利时社区环境中针对这个问题.
- 这种由药剂师主导的方法包括患者教育和处方者沟通工具.
研究的目的:
- 评估D-PRESCRIBE干预措施在比利时社区药房环境中的可行性.
- 评估一个集群随机对照试验设计的可行性,用于干预评估.
- 进行干预措施的探索性成本效益分析.
主要方法:
- 一个可行性集群随机对照试验,涉及8-10个社区药房和56-80名患者 (≥65岁).
- 干预药房提供了适应的D-PRESCRIBE程序;对照药房提供了通常的护理.
- 通过患者和药剂师问卷在基线,3个月和6个月收集的数据;通过定性访谈补充.
主要成果:
- 通过参与率,数据完整性和满意度调查,将评估D-PRESCRIBE干预和研究设计的可行性.
- 探索性成本效益分析和以患者为中心的结果将被审查.
- 定性数据将为患者和药剂师的经验提供洞察力.
结论:
- D-PRESCRIBE干预是一种可行的药剂师主导的策略,用于在比利时老年人中减少BZRA的处方.
- 该研究设计适合进行更大规模的,最终的试验,评估干预的有效性和成本效益.
- 调查结果将为未来的解药工作提供信息,并支持社区药房的基于证据的实践.
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