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Updated: May 24, 2025

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Z型DNA-RNA混合物阻断了DNA复制的发生

Shiyu Wang1, Yan Xu1

  • 1Division of Chemistry, Department of Medical Sciences, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan.

Nucleic acids research
|March 4, 2025
PubMed
概括

甲基化CpG重复形成Z型DNA-RNA混合体,通过抑制Okazaki片段形成来阻止DNA复制. 结构分析揭示了一个独特的齐克扎克模式,负责这种复制抑制.

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