来自果加工过程中受酶处理的侧流中的点氨酸衍生物寡糖的发酵特性
J W Zwolschen1, A P Vos2, R M C Ariëns2
1Wageningen University & Research, Laboratory of Food Chemistry, Bornse Weilanden 9, 6708 WG Wageningen, the Netherlands.
Carbohydrate polymers
|March 4, 2025
概括
果皮的废物可以转化为肠道友好的寡糖. 甲基化显著影响这些纤维的发酵方式,影响结肠沿线的肠道健康.
科学领域:
- 生物技术是生物技术.
- 微生物学 微生物学
- 营养科学 营养科学
背景情况:
- 汁加工产生了重要的侧流,例如皮废物.
- 来自植物纤维的可发酵寡糖 (OS) 对肠道健康有潜在的益处.
- 了解肠道微生物群对来自点的OS的发酵是优化其对健康的影响至关重要的.
研究的目的:
- 探索汁侧流转化为可发酵的寡糖.
- 为了研究由近端和远端肠道微生物群在体外发酵的点氨酸衍生的寡糖 (POS).
- 阐明甲基化在调节POS发酵性的作用及其对短链脂肪酸生产的影响.
主要方法:
- 皮废物经过酵素处理,使用解酶产生POS和非甲基化POS (POSNME).
- 在体外批量发酵中使用来自三个健康捐赠者的近端和远端微生物群进行.
- 分析了微生物发酵模式和短链脂肪酸生产.
主要成果:
- 无论是POS和POSNME混合物都是完全由肠道微生物群发酵的.
- 发酵产生了有益的短链脂肪酸:乙酸,酸和丁酸.
- POS的甲基化显著调节了它们的发酵能力,非甲基化的形式得到了更快的利用.
结论:
- 来自果皮的寡糖类是人类肠道微生物群的发酵.
- 碳水化合物的分子结构,特别是甲基化,在确定结肠沿线的发酵模式中起着关键作用.
- 消费各种可发酵纤维对于促进全面的肠道健康至关重要.
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