眼结核后的罕见双边角膜穿孔:一个病例报告和临床见解
Justin Dreyer1, Lauren Kiryakoza2, Jonathan Tijerina2
1Bascom Palmer Eye Institute, 900 NW 17 St, FL, Miami, 33136, USA. jtd139@miami.edu.
Journal of ophthalmic inflammation and infection
|March 4, 2025
概括
这一案例突出显示了双边角膜穿孔是由眼结核病引起的,这是一个罕见的疾病. 一个阳性干扰素γ释放试验 (IGRA) 证实了这个患者的诊断.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
背景情况:
- 眼结核是一种罕见的严重眼睛疾病的罕见原因.
- 双边角膜硬膜穿孔是一种非常罕见的表现.
研究的目的:
- 报告一种罕见的双边角膜穿孔病例.
- 为了调查Mycobacterium结核病感染在本报告中的作用.
- 要突出干扰素γ释放试验 (IGRA) 在诊断中的实用性.
主要方法:
- 一个27岁的患者的病例报告,双眼症状.
- 临床检查包括裂纹灯,视敏度 (VA) 和眼内压力 (IOP) 的测量.
- 图像:胸部X射线,脸部和鼻腔的CT.
- 实验室检测:IGRA,艾滋病毒,ACE,ANA,ANCA,CRP,抗硬质体抗体,HCV.
主要成果:
- 患者呈现了五个月的发红,疼痛和视力下降 (双边计数手指).
- 检查显示了双边羊肉脂肪的角质沉物,hypopyon和角膜穿孔 (西德尔阳性右眼,西德尔阴性左眼).
- 胸部X射线显示肺部溢液;CT显示双边球体变厚;IGRA呈阳性;其他工作是负面的.
结论:
- 这种病例证明了眼结核病中罕见的双边角膜参与.
- 及时诊断和使用抗结核疗法和皮质类固醇治疗至关重要.
- IGRA是诊断眼结核病的一个有价值的工具.
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