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Updated: Jun 15, 2025

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
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在新药开发中考虑动态工具的监管可重复使用性

Jiang Liu1, Yuching Yang1, Joga Gobburu2

  • 1Office of Clinical Pharmacology (OCP), Office of Translational Sciences (OTS), Center for Drug Evaluation and Research (CDER), Food and Drug Administration (FDA), 10903 New Hampshire Ave, Silver Spring, MD, 20993, USA.

Pharmaceutical research
|March 4, 2025
PubMed
概括

基于模型的药物开发 (MIDD) 使用动态工具,如人口药动力学 (popPK) 和生理基础药动力学 (PBPK) 模型. 模型主文件 (MMF) 框架旨在改善模型共享和监管接受,以提高药物开发效率.

关键词:
建模 建模模型 建模模型可重复使用性可重复使用性.模拟模拟是指一个模拟模拟.研讨会报告 研讨会报告

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