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对PAP-PCR方法在检测UGT1A1基因多态化中的性能进行评估

Xiangsha Kong1, Bo Feng1, Zixiang Huang2

  • 1Peking University People's Hospital, Peking University Hepatology Institute, Infectious Disease and Hepatology Center of Peking University People's Hospital, Beijing Key Laboratory of Hepatitis C and Immunotherapy for Liver Diseases, Beijing International Cooperation Base for Science and Technology On NAFLD Diagnosis, Beijing, 100044, China.

Molecular biology reports
|March 4, 2025
PubMed
概括

活化聚合物激活PCR (PAP-PCR) 有效检测UGT1A1基因多态性,用于吉尔伯特综合征的诊断. 与直接测序相比,这种方法在TA重复序列方面显示出更高的准确性,这使得它成为一种有利的临床选择.

关键词:
吉尔伯特综合征 (GS) 是一种活化聚合PCR (PAP-PCR) 是一种活化聚合PCR.尿素二酸糖诺西尔转移酶1A1 (UGT1A1) 是一种

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