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Updated: May 24, 2025

Induction of Murine Intestinal Inflammation by Adoptive Transfer of Effector CD4+CD45RBhigh T Cells into Immunodeficient Mice
08:37

Induction of Murine Intestinal Inflammation by Adoptive Transfer of Effector CD4+CD45RBhigh T Cells into Immunodeficient Mice

Published on: April 21, 2015

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RNA细胞氨基酸转移酶NAT10维持T细胞在炎症性肠病中的致病性

Haixin Li1,2,3, Xuemin Cai4, Changfen Xu2,3

  • 1Tongji University Cancer Center, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.

Cell discovery
|March 4, 2025
PubMed
概括

N-乙转移酶10 (NAT10) 调节炎性肠病 (IBD) 中的T细胞平衡. 它的缺乏会损害T细胞的发育,并通过破坏Bag3基因的稳定性来促进细胞亡,这表明RNAac4C修饰是潜在的IBD疗法.

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