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Updated: May 24, 2025

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CTDP1和RPB7稳定了Pol II,并允许重新启动

Haonan Zheng1, Qiqin Xu1, Dexun Ji1

  • 1State Key Laboratory of Gene Function and Modulation Research, Key Laboratory of Cell Proliferation and Differentiation of the Ministry of Education, Beijing Advanced Center of RNA Biology (BEACON), School of Life Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China.

Nature communications
|March 4, 2025
PubMed
概括

RPB7的耗尽使RNA聚合酶II (Pol II) 亚单元RPB1.1不稳定. RPB7招募酸酶CTDP1来稳定Pol II,这对于转录重启和RNA处理至关重要.

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