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Updated: May 24, 2025

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform
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ViLR:一种新的虚拟长读法,用于在没有试验对象的情况下,在新的PGT-SR载体中识别断点和直接SNP单双类型

Jiangyang Xue1,2,3, Min Xie1,2,3, Jie Cai4

  • 1The Central Laboratory of Birth Defects Prevention and Control, The Affiliated Women and Children's Hospital of Ningbo University, Ningbo, Zhejiang, 315012, China.

Reproductive biology and endocrinology : RB&E
|March 4, 2025
PubMed
概括

一种新的虚拟长读测序方法 (ViLR) 能够准确识别断点,并直接确定SNP类型,用于在新染色体结构重排序 (CSR) 的家族中进行结构重排序 (PGT-SR) 的植入前遗传测试. 这种方法克服了当前方法的局限性,在没有试验参与的情况下提供了临床潜力.

关键词:
在新的一次.断点识别 断点识别直接的SNP单双类型化进行结构重组的植入前遗传测试 (PGT-SR).基于虚拟NGS的长读方法 (ViLR)

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