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Updated: May 24, 2025

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
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与阿尔茨海默病和其他常见的与年龄相关的临床和神经病理学特征相关的结构变异

Ricardo A Vialle1, Katia de Paiva Lopes2, Yan Li2

  • 1Rush Alzheimer's Disease Center, Rush University Medical Center, 1750 W Harrison St, Chicago, IL, 60612, USA. ricardo_a_vialle@rush.edu.

Genome medicine
|March 5, 2025
PubMed
概括

结构变异 (SV) 有助于解释阿尔茨海默病 (AD) 的遗传风险. 在TMEM106B中删除与AD表型密切相关,揭示了对神经退行性疾病机制的新见解.

关键词:
阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.认知能力下降 认知能力下降在GWAS中,GWAS就是GWAS.结构变体 结构变体在WGS中,使用的是WGS.

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