相关实验视频

Updated: May 24, 2025

Development of a Human Preclinical Model of Osteoclastogenesis from Peripheral Blood Monocytes Co-cultured with Breast Cancer Cell Lines
06:00

Development of a Human Preclinical Model of Osteoclastogenesis from Peripheral Blood Monocytes Co-cultured with Breast Cancer Cell Lines

Published on: September 13, 2017

7.0K

MiR-147b-3p通过准NDUFA4和PI3K/AKT通路来促进骨质生成

Yuanyuan Guo1,2, Kai Shen3, Zhijie Li2

  • 1Chongqing Medical University, Chongqing, 400016, China.

Journal of orthopaedic surgery and research
|March 5, 2025
PubMed
概括

微RNA-147b-3p (miR-147b-3p) 通过向NDUFA4.4来促进骨质疏松性脊椎压缩骨折 (OVCF) 的骨质形成. 这项研究揭示了miR-147b-3p作为OVCF治疗的潜在治疗标.

关键词:
在 MiR-147b-3p 里面.骨质发生性脊椎压缩骨折 (OVCF)酸氨基 3-激酶 (PI3K) /AKT通路第一种类型的共酶脱酶1α亚复合物4 (NDUFA4)

更多相关视频

Stimulation of Notch Signaling in Mouse Osteoclast Precursors08:01

Stimulation of Notch Signaling in Mouse Osteoclast Precursors

Published on: February 28, 2017

7.8K
Improved Methodology for Studying Postnatal Osteogenesis via Intramembranous Ossification in a Murine Bone Marrow Injury Model05:10

Improved Methodology for Studying Postnatal Osteogenesis via Intramembranous Ossification in a Murine Bone Marrow Injury Model

Published on: February 7, 2025

280

相关概念视频

PI3K/mTOR/AKT Signaling Pathway01:22

PI3K/mTOR/AKT Signaling Pathway

The mammalian target of rapamycin  (mTOR) is a serine/threonine kinase that regulates growth, proliferation, and cell survival in response to hormones, growth factors, or nutrient availability. This kinase exists in two structurally and functionally distinct forms: mTOR complex 1  (mTORC1) and mTOR complex 2  (mTORC2). The first form (mTORC1) is composed of a rapamycin-sensitive Raptor and proline-rich Akt substrate, PRAS40. In contrast,  mTORC2 consists of a...
3.4K
mTOR Signaling and Cancer Progression03:03

mTOR Signaling and Cancer Progression

The mammalian target of rapamycin or mTOR protein was discovered in 1994 due to its direct interaction with rapamycin. The protein gets its name from a yeast homolog called TOR. The mTOR protein complex in mammalian cells plays a major role in balancing anabolic processes such as the synthesis of proteins, lipids, and nucleotides and catabolic processes, such as autophagy in response to environmental cues, such as availability of nutrients and growth factors.
The mTOR pathway or the...
3.7K