相关实验视频

Updated: Jul 22, 2026

Scalable High Throughput Selection From Phage-displayed Synthetic Antibody Libraries
12:55

Scalable High Throughput Selection From Phage-displayed Synthetic Antibody Libraries

Published on: January 17, 2015

18.5K

一个利用蛋白质语言模型的抗体开发能力分类管道

James Sweet-Jones1, Andrew C R Martin1

  • 1Institute of Structural and Molecular Biology, Division of Biosciences, University College London, London, UK.

mAbs
|March 5, 2025
PubMed
概括

这项研究引入了一种机器学习管道,以识别具有有利可开发性特征的治疗单克隆抗体 (mAbs). 该方法使用蛋白质语言模型在发育早期选择有前途的抗体候选者,降低成本并提高成功率.

关键词:
抗体是一种抗体.开发能力 开发能力机器学习是机器学习.预测 预测 预测 预测蛋白质语言模型的模型

更多相关视频

Kinase Inhibitor Screening In Self-assembled Human Protein Microarrays13:22

Kinase Inhibitor Screening In Self-assembled Human Protein Microarrays

Published on: October 23, 2019

7.8K
Cell-Free Production of Proteoliposomes for Functional Analysis and Antibody Development Targeting Membrane Proteins08:46

Cell-Free Production of Proteoliposomes for Functional Analysis and Antibody Development Targeting Membrane Proteins

Published on: September 22, 2020

3.7K

相关概念视频

Leaky Scanning02:28

Leaky Scanning

During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA.  Marilyn Kozak discovered that the sequence RCCAUGG (where R stands for...