穿戴式加速胸膜扫描用于动脉脉压监测:一个可行性研究
概括
一个新的可穿戴传感器系统使用加速度计来跟踪动脉脉压和缩血压. 这种非侵入性设备显示出强烈的相关性和可靠的测量,为持续的中央血压监测提供了潜力.
科学领域:
- 生物医学工程 生物医学工程
- 心血管生理学心血管生理学
- 可穿戴技术可穿戴技术
背景情况:
- 中枢血压 (CBP) 比周围血压更好地预测器官损伤.
- 目前的CBP估计方法复杂,需要校准,不适合持续监测.
研究的目的:
- 推出一种基于加速度计的可穿戴系统,用于跟踪动脉脉压 (PP).
- 评估使用该系统用于门诊中央血压评估的可行性.
主要方法:
- 一个可穿戴系统被开发用于检测穿皮压力 (PT) 在动脉上使用加速度计.
- 在体内对11名受试者进行实验,以将PT参数 (ΔPT,g2) 与大脑动脉PP和SBP相关联.
- 评估过皮压信号的可靠性 (SNR) 和可重复性 (CoV).
主要成果:
- 峰值对峰值的ΔPT和最大g2显示出与大脑动脉PP (r=0.75) 和SBP (r=0.78),分别有很强的相关性.
- 与心血管PP和SBP相比,PT参数对运动的响应幅度显著更高.
- 该系统显示出高可靠性 (SNR> 38 dB) 和可重复性 (CoV < 10%).
结论:
- 一个基于可穿戴加速囊图 (APG) 的系统可以切实跟踪带PP和SBP的变化.
- 这项技术有望开发可穿戴系统,用于在临床和家庭环境中持续的门诊中央血压监测.
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