对肺癌切除后术后肺功能预测因素的系统审查和元分析
Hongling Wang1, Lihong He2, Xiaoyun Hu3
1Department of Interventional Surgery, Yantaishan Hospital, Yantai City, China.
概括
计算机断层扫描 (CT) 的体积和密度测量是预测术后肺功能,特别是1秒内强制呼气体积 (FEV1) 的最准确方法. 这一发现有助于选择患者接受肺癌手术.
科学领域:
- 肺部医学 肺部医学
- 放射学 放射学是一门学科.
- 手术瘤学手术瘤学
背景情况:
- 肺切除是早期肺癌的主要治疗方法.
- 术后肺功能的准确预测对于手术资格和治疗术后呼吸道并发症至关重要.
研究的目的:
- 在临床实践中识别和比较用于预测术后肺功能的常用方法的准确性.
主要方法:
- 进行了对10项研究的系统审查和元分析.
- 柯克兰偏差风险工具评估了研究质量.
- 进行了预测与测量1秒内强制呼气体积 (FEV1) 的平均差异的元分析.
- 出版偏差是使用漏斗图和Begg测试来评估的.
主要成果:
- 包含的研究具有偏差的低风险.
- 计算机断层扫描 (CT) 的体积和密度测量在预测术后FEV1.1方面表现出最高的准确性.
- 预测和实际FEV1之间的平均差异为83毫升 (95% CI,41-116).
结论:
- CT体积和密度测量是预测术后FEV1.1的最佳方法.
- 需要进一步的研究来关联外科手术程序,门和患者的结果.
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