邻居环境,产前接触酒精和烟草,以及结构性大脑发育之间的关联
Yingjing Xia1, Verónica M Vieira1
1Joe C. Wen School of Population and Public Health, Susan and Henry Samueli College of Health Sciences, University of California, Irvine, Irvine, CA, United States.
Frontiers in human neuroscience
|March 5, 2025
概括
邻居环境会影响孩子的大脑发育,尤其是海马体积. 产前吸烟可能会改变这种关系,这表明影响大脑结构的复杂相互作用.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 环境健康 环境健康
背景情况:
- 产前接触酒精和烟草会对儿童大脑发育产生负面影响.
- 邻居环境对结构性大脑发育的影响及其与产前暴露的相互作用尚未得到充分理解.
研究的目的:
- 研究9-11岁儿童邻居环境与大脑容量之间的关联.
- 为了确定产前酒精或烟草暴露是否会改变邻居环境和大脑发育之间的关系.
主要方法:
- 从7887名青少年大脑和认知发展 (ABCD) 研究参与者的基线数据分析.
- 使用10个变量对邻居环境的描述和产前酒精/烟草暴露的评估.
- 检查海马,准海马和内腔区域的双边体积.
主要成果:
- 高居住区贫困与较小的右海马体积相关.
- 产前酒精暴露与较大的左侧副海马和海马体积有关.
- 产前烟草暴露与双边副海马体,右内体和右海马体区域的体积较小有关.
- 在没有产前接触烟草的儿童中,邻居剥夺与较小的右海马体积有关,但在接触烟草的儿童中并非如此.
结论:
- 邻居环境显著影响儿童大脑发育,特别是海马体积.
- 产前吸烟似乎改变了邻居环境和大脑结构之间的关联.
- 未来的研究应该探索产前吸烟和产后邻居环境对大脑发育的相互作用.
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