那不勒斯预后得分作为严重腹腔大动脉化的新预测指数:基于人口的研究
Qiang Tan1, Jian Zhang1, Yanrong Peng1
1Vascular Surgery, Affiliated Hospital of North Sichuan Medical College, Nanchong Sichuan, China.
Frontiers in cardiovascular medicine
|March 5, 2025
概括
那不勒斯预后得分 (NPS) 与严重的腹腔大动脉化 (SAAC) 有关. 较高的NPS分数表明SAAC的风险更高,表明其作为诊断标记物的潜力.
科学领域:
- 心血管健康 心血管健康
- 炎症生物标志物 炎症生物标志物
- 营养状况评估 营养状况评估
背景情况:
- 腹腔大动脉化 (AAC) 与全身炎症和营养状况有关.
- 那不勒斯预后得分 (NPS) 是一种反映炎症和营养状况的新标记.
研究的目的:
- 调查那不勒斯预后得分 (NPS) 和严重腹腔大动脉化 (SAAC) 之间的相关性.
主要方法:
- 利用了2013-2014年国家健康和营养检查调查 (NHANES) 的数据.
- 使用LASSO回归来选择变量和加权后勤回归来分析NPS-SAAC关联.
- 使用接收器运行特征 (ROC) 曲线和进行的子组分析评估预测值.
主要成果:
- 在2854名参与者中,303人 (11.87%) 患有SAAC.
- 3至4个点的NPS显示出与SAAC的正相关性 (OR=2.07,95% CI:1.17-3.67).
- 预测SAAC风险的NPSROC曲线下的面积为0.635;子组分析没有发现显著差异.
结论:
- 观察到NPS和SAAC之间的积极关联.
- NPS可以为SAAC的预防和诊断提供见解.
- 需要进一步的纵向研究来确认因果关系和临床效用.
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