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在早产新生儿中使用低分子量肝素后,严重的血瘤

Naveed Ur Rehman Durrani^1,2, Elhindi Elfaki¹, Nqobile Tessa Sigola¹

¹Division of Neonatology, Department of Pediatrics, Sidra Medicine, Doha, Qatar.

Case reports in perinatal medicine

|March 5, 2025

概括

低分子量肝素 (LMWH) 在患有血栓栓塞的早产儿中使用可以导致严重的血瘤. 密切监测注射部位对于管理新生儿这些风险至关重要.

科学领域:

新生儿医学新生儿医学
儿科血液学儿科血液学
血栓形成的管理

背景情况:

血栓栓塞栓 (TE) 事件越来越多地在早产新生儿中被发现,这是由于内置导管.
在这种人群中,低分子量肝素 (LMWH) 对TE事件的使用是有争议的,关于其安全性和有效性的数据有限.
在早产婴儿中LMWH的药理动力学和治疗水平是可变的.

研究的目的:

在LMWH给药后,在早产新生儿中呈现严重的血瘤病例.
强调监测新生儿LMWH注射部位的重要性.

主要方法:

案例报告的呈现方式.
对临床管理和结果的审查.

主要成果:

一名早产新生儿在为TE事件接受LMWH治疗后发展出严重的大腿血瘤.
血瘤需要手术排水和成功的皮肤移植.

结论:

在早产新生儿中,对LMWH注射部位的早期和警监测至关重要.
这一案例强调了LMWH在这个脆弱人群中的潜在并发症.
仔细观察可以帮助及时检测和管理不良事件.

关键词:

非常低的出生体重婴儿婴儿血腫血腫血腫血腫低分子量肝素是什么

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