听力损失与儿童艾滋病毒的关联
Deepika Acharya1, Alok Hemal2, Chetan S Tanwar3
1Department of Pediatrics, Vardhman Mahavir Medical College and Safdarajung Hospital, New Delhi, IND.
Cureus
|March 5, 2025
概括
听力损失 (HL) 影响16.67%的人类免疫缺陷病毒 (HIV) 的儿童. 这种导电性听力损失与艾滋病毒严重程度的增加相关,强调需要对艾滋病毒阳性儿童进行听力学查.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 听力学 听力学是指听力学.
背景情况:
- 患有人类免疫缺陷病毒 (HIV) 的儿童面临着各种健康挑战.
- 听力损失 (HL) 是一个需要调查的潜在并发症.
- 早期发现和治疗HL对于儿童整体发育至关重要.
研究的目的:
- 确定艾滋病毒感染儿童听力损失 (HL) 的发生率.
- 评估HL和HIV疾病持续时间和严重程度之间的关联.
- 评估HL与CD4计数和病毒载荷的相关性.
主要方法:
- 一项涉及60名5-18岁艾滋病毒阳性儿童的横截面研究.
- 纯色调听力测量用于查和评估听力损失.
- 统计分析包括曼-惠特尼,费舍尔的精确和独立的t测试 (p < 0.05).
主要成果:
- 16.67%的艾滋病毒感染儿童有听力损失,所有都是导电的.
- HL主要是轻微的,通常是单边的.
- 较低的CD4计数和较高的病毒载量与HL显著相关 (p <0.05).
结论:
- 听力损失是艾滋病毒感染儿童的一个重大问题,与疾病严重程度相关.
- 建议对所有艾滋病毒阳性儿童进行例行听力学查.
- 及时的听力学援助可以改善受影响儿童的结果.
相关概念视频
Immunodeficiency Diseases
890
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
There are three main causes of immunodeficiency...
890
Sexually Transmitted Infections
256
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
256
Hearing
51.7K
When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.
51.7K
Pulmonary Tuberculosis I
215
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
215
Retrovirus Life Cycles
45.5K
Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
45.5K


