广州过敏性鼻炎儿童的气体过敏剂敏感化模式和相关因素
Qingxiang Zeng1, Chao Yang1, Jinyuan Li1
1Department of Otolaryngology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, China.
Mediators of inflammation
|March 5, 2025
概括
粉尘仍然是过敏性鼻炎 (AR) 儿童的主要过敏原. 在COVID-19后,对德国,猫和狗的敏感性增加,突出显示了不断变化的过敏原模式.
科学领域:
- 儿科过敏和免疫学
- 环境过敏原 环境过敏原
- 过敏疾病的流行病学
背景情况:
- 患有过敏性鼻炎 (AR) 的儿童的血清免疫球蛋白E (IgE) 敏感化模式可以预测疾病的进展.
- 了解空气过敏原敏感性的时间变化对于管理儿科AR至关重要.
研究的目的:
- 分析十年来AR儿童对气体过敏原敏感性的趋势.
- 为了比较COVID-19大流行前后的敏感化模式.
主要方法:
- 对九种空气过敏原的血清IgE水平的回顾性分析.
- 这项研究包括21362名1至12岁的AR儿童.
- 从广州妇女和儿童医疗中心收集的数据 (2013年6月-2023年6月).
主要成果:
- 粉尘 (*Dermatophagoides farinae* 和 *Dermatophagoides pteronyssinus*) 是最常见的过敏原.
- 在COVID-19后,对德国,猫和狗的敏感性增加; *D. pteronyssinus*略有下降.
- 学龄儿童对大多数过敏原的敏感度比学龄前儿童高.
结论:
- 避免 *Dermatophagoides farinae* 和 *Dermatophagoides pteronyssinus* 在减少AR发作方面仍然至关重要.
- 变化的过敏原敏感化模式需要更新儿科过敏性鼻炎的管理策略.
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