医学科学学生在症状学培训计划后接种COVID-19疫苗后自我报告的不良事件:一个跨部门研究
Taraneh Tavanaei Tamanaei1, Mohammad Bagher Oghazian2,3, Mehran Mojtabaee4
1Lung Diseases Research Center Mashhad University of Medical Sciences Mashhad Iran.
Health science reports
|March 5, 2025
概括
与Sinopharm COVID-19疫苗相比,Oxford-AstraZeneca的第一剂后的不良事件 (AE) 更常见. 性别和疫苗类型影响了AE患病率,女性患病率更高.
科学领域:
- 医学科学 医学科学 医学科学
- 疫苗学 疫苗学 疫苗学
- 公共卫生 公共卫生
背景情况:
- 在接种COVID-19疫苗后对不良事件 (AE) 的准确调查对于公众的信任至关重要.
- 这项研究评估了医学学生中COVID-19疫苗相关的AE.
研究的目的:
- 为了评估和比较牛津-阿斯特拉泽内卡 (AZD1222) 和Sinopharm (BBIBP-CorV) COVID-19疫苗后AEs的患病率.
- 确定影响AE发生的因素.
主要方法:
- 一项涉及263名医学科学学生的横截面研究.
- 通过谷歌表单进行自我管理的调查被用来收集数据.
- 实施了一项培训计划,以尽量减少AE报告中的确认偏差.
主要成果:
- 牛津-阿斯特拉泽内卡的第一剂与明显高于Sinopharm的AE患病率有关 [OR 12.93].
- 在第二剂后的疫苗之间没有观察到AE患病率的显著差异 [OR 1.45].
- 常见的副作用包括注射部位疼痛,发烧,身体/肌肉疼痛,头痛,疲劳;女性报告的副作用的几率更高.
结论:
- 牛津-阿斯特拉泽内卡疫苗的AE患病率高于Sinopharm,特别是在第一剂后.
- 疫苗类型和性别是影响AE发生的重要因素.
- 需要对COVID-19疫苗AE进行标准化定义,以实现一致的报告.
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