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Updated: May 24, 2025

Detection of Inflammasome Activation and Pyroptotic Cell Death in Murine Bone Marrow-derived Macrophages
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在大肠炎中,PGAM5-NEK7相互作用是NLRP3炎症酶激活的治疗标

Cheng-Long Gao1,2, Jinqian Song1, Haojie Wang1

  • 1State Key Laboratory of Natural Medicines, New Drug Screening Center, Key Laboratory of Drug Quality Control and Pharmacovigilance (Ministry of Education), China Pharmaceutical University, Nanjing 210009, China.

Acta pharmaceutica Sinica. B
|March 5, 2025
PubMed
概括

缺乏PGAM5的小鼠通过抑制NLRP3炎症酶激活来减少性结肠炎的严重程度. PGAM5-NEK7相互作用驱动着炎症酶激活,为结肠炎提供了治疗点.

关键词:
在APEX2近距离标签上.大肠炎是什么意思巨细胞是一个巨细胞.在NEK7中,NEK7是NEK7.在NLRP3炎症酶组中,这是一个PGAM5PGAM5.蛋白质蛋白质相互作用在Punicalagin中使用.

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