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Updated: May 24, 2025

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
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模态天然产品panepocyclinol A通过二共价修饰抑制STAT3

Li Li1,2,3, Yuezhou Wang1,2,3, Yiqiu Wang4

  • 1State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen 361102, China.

Acta pharmaceutica Sinica. B
|March 5, 2025
PubMed
概括

帕内波环醇A (PecA) 是一种新的STAT3抑制剂,具有强大的抗瘤作用. 这种二次化合物破坏了STAT3DNA结合和转录活动,为像T细胞淋巴瘤这样的癌症提供了新的治疗策略.

关键词:
无形成性大T细胞淋巴瘤在二共价变化修改中.二元化合物是二元化合物.模度化 (Dimerization) 是一个过程.自然产品是一种自然产品.帕内波环醇A是一种这是一种STAT3抑制剂.信号传感器和转录激活器 3 3

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