Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Brain Imaging01:14

Brain Imaging

202
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
202
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

4.9K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
4.9K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

An H<sub>2</sub>O<sub>2</sub> activated Ag<sub>2</sub>S:In-Cu nanoprobe for <i>in vitro</i> synergistic tumor treatment.

Nanoscale·2025
Same author

MiR-30c suppresses the proliferation, metastasis and polarity reversal of tumor cell clusters by targeting MTDH in invasive micropapillary carcinoma of the breast.

Heliyon·2024
Same author

Engineering miniature IscB nickase for robust base editing with broad targeting range.

Nature chemical biology·2024
Same author

The circular RNA circSLC16A10 alleviates diabetic retinopathy by improving mitochondrial function via the miR-761-5p/MFN2 axis.

Cellular signalling·2024
Same author

Tailored interface engineering of Co<sub>3</sub>Fe<sub>7</sub>/Fe<sub>3</sub>C heterojunctions for enhancing oxygen reduction reaction in zinc-air batteries.

Journal of colloid and interface science·2024
Same author

Retinoschisin Is Required for Pineal Gland Calcification and Cellular Communication in Pinealocytes of Rats and Mice.

Laboratory investigation; a journal of technical methods and pathology·2024

相关实验视频

Updated: May 24, 2025

Functional Near Infrared Spectroscopy of the Sensory and Motor Brain Regions with Simultaneous Kinematic and EMG Monitoring During Motor Tasks
11:31

Functional Near Infrared Spectroscopy of the Sensory and Motor Brain Regions with Simultaneous Kinematic and EMG Monitoring During Motor Tasks

Published on: December 5, 2014

15.1K

通过NIR-II成像对大脑进行动态病理生理洞察.

Si Chen1,2, Hao Chen2,3, Xinxin Li3

  • 1Department of Neurology, Xiangya Hospital, Central South University, Xiangya Road 88, Changsha, 410008, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|March 5, 2025
PubMed
概括

新的有机纳米探测器使大脑血流和血脑屏障完整性的详细体内成像成为可能. 这一进展有助于对神经疾病和潜在干预措施的理解.

关键词:
BBB 干扰 BBB 的干扰在NIR-II光中,光效应大脑附带循环的循环.结晶的有机纳米探测器实体脑部成像 实体脑部成像

更多相关视频

Non-invasive Parenchymal, Vascular and Metabolic High-frequency Ultrasound and Photoacoustic Rat Deep Brain Imaging
12:00

Non-invasive Parenchymal, Vascular and Metabolic High-frequency Ultrasound and Photoacoustic Rat Deep Brain Imaging

Published on: March 2, 2015

12.1K
Simultaneous Evaluation of Cerebral Hemodynamics and Light Scattering Properties of the In Vivo Rat Brain Using Multispectral Diffuse Reflectance Imaging
07:06

Simultaneous Evaluation of Cerebral Hemodynamics and Light Scattering Properties of the In Vivo Rat Brain Using Multispectral Diffuse Reflectance Imaging

Published on: May 7, 2017

7.6K

相关实验视频

Last Updated: May 24, 2025

Functional Near Infrared Spectroscopy of the Sensory and Motor Brain Regions with Simultaneous Kinematic and EMG Monitoring During Motor Tasks
11:31

Functional Near Infrared Spectroscopy of the Sensory and Motor Brain Regions with Simultaneous Kinematic and EMG Monitoring During Motor Tasks

Published on: December 5, 2014

15.1K
Non-invasive Parenchymal, Vascular and Metabolic High-frequency Ultrasound and Photoacoustic Rat Deep Brain Imaging
12:00

Non-invasive Parenchymal, Vascular and Metabolic High-frequency Ultrasound and Photoacoustic Rat Deep Brain Imaging

Published on: March 2, 2015

12.1K
Simultaneous Evaluation of Cerebral Hemodynamics and Light Scattering Properties of the In Vivo Rat Brain Using Multispectral Diffuse Reflectance Imaging
07:06

Simultaneous Evaluation of Cerebral Hemodynamics and Light Scattering Properties of the In Vivo Rat Brain Using Multispectral Diffuse Reflectance Imaging

Published on: May 7, 2017

7.6K

科学领域:

  • 神经科学是一个神经科学.
  • 生物医学工程 生物医学工程
  • 材料科学 材料科学 材料科学

背景情况:

  • 大脑附带循环和血脑屏障 (BBB) 对大脑功能至关重要.
  • 目前的诊断工具在评估动态神经血管单元功能方面存在局限性.
  • 了解疾病中的附带输液和BBB变化是有限的.

研究的目的:

  • 开发和评估用于体内脑血管成像的新型纳米探针.
  • 评估这些纳米探针在可视化抵押流通和BBB完整性的潜力.
  • 探索神经疾病模型中的应用.

主要方法:

  • 从小分子染料和牛血清白蛋白中合成高晶半导体有机纳米探针 (4T-BSA).
  • 在第二个近红外窗口 (NIR-II,1000-1700nm) 中的活体大脑血管成像.
  • 在小鼠模型中评估成像透深度,信号与背景比率 (SBR) 和空间分辨率.

主要成果:

  • 4T-BSA纳米探针在完整的小鼠大脑中显示出优异的成像透深度.
  • 获得高SBR (6.0) 和50μm以下的大脑血管的空间分辨率.
  • 在神经疾病模型中成功可视化了血管附带输液和白蛋白泄漏.
  • 确定了与抵押流网络和BBB中断相关的病态活动.

结论:

  • 4T-BSA纳米探针在NIR-II窗口中对活脑血管成像非常有效.
  • 这些纳米探针为大脑附带循环和BBB完整性提供了宝贵的见解.
  • NIR-II成像对推进神经疾病的诊断和治疗具有前途.