冠心病作为老年COVID-19患者妄的危险因素
Young-Gun Lee1, Sang-Won Park2, Jihwan Bang2
1Department of Neurology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.
Geriatrics & gerontology international
|March 5, 2025
概括
患有冠心病的COVID-19的老年患者面临更高的 Delirium 风险. 这些患者的妄想与COVID-19的较差结果和对重症监护的需求增加有关.
科学领域:
- 老年医学 老年医学
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- 在急性感染,特别是COVID-19中,妄与不良结果有关.
- 在异质感染人群中对妄风险因素的研究是有限的.
- 识别高风险患者对于及时干预至关重要.
研究的目的:
- 为了确定患有COVID-19住院的老年患者 Delirium 的危险因素.
- 分析临床和实验室特征与妄相关的这个人口群体.
- 了解妄对老年人COVID-19结果的影响.
主要方法:
- 韩国一家COVID-19指定医院的回顾性研究 (2020年2月 - 2022年5月).
- 对75岁以上的COVID-19患者的临床和实验室数据的分析.
- 二元逻辑回归用于识别妄的显著风险因素.
主要成果:
- 在1166名老年COVID-19患者中,4.5%的人患有 Delirium.
- 患有妄想症的患者更有可能从其他医院转移,并且体温更高.
- 冠心病 (CHD) 病史和较高的C-反应蛋白水平与妄想显著相关.
- 妄想与增加需要氧气支持,机械通风和更高层次的护理有关.
- 在多重回归模型中,心脏病显示出神妄的几率比率 (2.898) 显著更高.
结论:
- 冠心病是老年COVID-19患者妄的重要危险因素.
- 痴呆症与更糟糕的COVID-19结果和该人口中医疗资源利用率的增加有关.
- 在老年COVID-19患者中早期发现心血管疾病可能有助于妄风险分层.
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