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相关概念视频

Altered States of Awareness01:06

Altered States of Awareness

145
Altered states of consciousness represent significant deviations from one's normal mental state. These deviations can range from subtle changes in awareness to profound transformations in perception, thought processes, and sensory experiences. Altered states of consciousness can be triggered by various factors, including drug use, meditation, hypnosis, illness, or even intense fatigue.
The ingestion of substances like stimulants or hallucinogens leads to chemical alterations in the brain...
145
CNS Stimulants: Cocaine, Amphetamines and Cannabinoids01:24

CNS Stimulants: Cocaine, Amphetamines and Cannabinoids

152
CNS stimulants, such as cocaine, amphetamines, and cannabinoids, have varying structures and mechanisms of action that lead to different therapeutic effects and side effects. Cocaine, with its molecular formula C17H21NO4, is a tropane alkaloid and a tertiary amino compound. It has two chemical forms: the hydrochloride salt and the "freebase." The former is in powder form, while the latter involves removing the hydrochloride salt to create a form that can be smoked. Cocaine exerts its...
152
Hallucinogens and Psychedelics01:27

Hallucinogens and Psychedelics

151
Hallucinogens are psychoactive substances that profoundly alter perceptual experiences, generating unreal visual and sensory images. Often referred to as psychedelic drugs — a term derived from the Greek words "psyche" (mind) and "delos" (revealing) — these substances include marijuana and lysergic acid diethylamide (LSD), among others. These drugs vary in intensity and effects.
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains...
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相关实验视频

Updated: May 24, 2025

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
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改变的功能连接动态服务于常规大麻使用者的认知灵活性.

Kellen M McDonald1,2, Mikki Schantell1,3, Jason A John1

  • 1Institute for Human Neuroscience, Boys Town National Research Hospital, Omaha, Nebraska, USA.

Addiction biology
|March 5, 2025
PubMed
概括
此摘要是机器生成的。

长期使用大麻会改变与认知灵活性相关的大脑连接. 这项研究发现,与非使用者相比,大麻使用者在任务切换期间大脑网络如何连接的差异.

关键词:
在MEGEG中,MEG是MEG.注意力网络注意力网络磁脑脑摄影 (MEG) 是一种磁脑脑摄影技术.振荡的振荡是如何发生的任务交换机 任务交换机

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科学领域:

  • 神经科学是一个神经科学.
  • 认知科学 认知科学
  • 精神病学是一个精神病学.

背景情况:

  • 大麻使用很常见,但其对诸如认知灵活性之类的执行功能的影响尚不清楚.
  • 了解慢性大麻使用者的认知灵活性的神经基础至关重要.

研究的目的:

  • 研究慢性大麻使用对认知灵活性的影响.
  • 在任务切换过程中检查底层的功能连接动态.

主要方法:

  • 利用磁脑电图 (MEG) 来记录25名慢性大麻使用者和30名非使用者的大脑活动.
  • 采用任务切换范式来评估认知灵活性,并分析神经振荡反应和全脑连接.
  • 功能连接切换成本与行为切换成本相关联,并比较了群体差异.

主要成果:

  • 在行为方面,所有参与者在交换试验中表现出更慢的反应时间.
  • 大麻使用者在功能连接切换成本和行为切换成本之间显示出改变的关联.
  • 这些变化在连接视觉皮层和腹部注意网络的途径沿线观察到,跨越泰达,α和马频段.

结论:

  • 慢性大麻使用与功能连接和行为转换成本之间的修改的多谱关联有关.
  • 这些修改涉及视觉皮层和对执行功能至关重要的大脑区域.
  • 这些发现突出了与慢性大麻消费相关的认知灵活性的神经生物学差异.