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Updated: May 24, 2025

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors
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伊斯拉特拉维尔在中度肝功能障碍参与者的药理动力学

Randolph P Matthews1, Munjal Patel1, Wen Liu1

  • 1Merck & Co., Inc., Rahway, New Jersey, USA.

Antimicrobial agents and chemotherapy
|March 5, 2025
PubMed
概括

伊斯拉特拉维尔 (ISL) 药理学在中度肝功能障碍患者中进行了评估. 观察到ISL及其代谢物M4的适度变化,这表明ISL在这个人群中通常耐受良好.

关键词:
肝功能受损 肝功能受损 肝功能受损人类免疫缺陷病毒人类免疫缺陷病毒这是latravir的岛屿.肝脏疾病是一种肝脏疾病.药物动力学 药物动力学

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