儿童肝脏脂肪评估的MRI和超声波:技术和支持证据
Suraj D Serai1,2, Manish Dhyani3, Saubhagya Srivastava3
1Department of Radiology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Journal of magnetic resonance imaging : JMRI
|March 5, 2025
概括
量化MRI和超声波方法可以准确地测量儿童的肝脂肪. 这些技术对于诊断与代谢功能障碍相关的脂肪性肝病 (MASLD) 和指导临床管理是有价值的.
科学领域:
- 放射学 放射学是一门学科.
- 儿科胃肠病学 儿科胃肠病学
- 医疗成像医学成像
背景情况:
- 肝硬化是慢性肝病的常见症状,通常与代谢功能障碍相关的肝硬化病 (MASLD) 相关.
- 准确量化肝脂肪对于诊断和管理至关重要.
- 基于MRI的质子密度脂肪分数 (PDFF) 是黄金标准,但超声波提供了可访问的定量替代方案.
研究的目的:
- 审查和指导使用MRI和基于超声波的脂肪量化技术来评估儿童肝硬化症.
- 讨论在儿科环境中优化这些方法的实际策略.
- 提供有关解释,报告和潜在陷的指导.
主要方法:
- 审查当前的MRI技术,专注于质子密度脂肪分数 (PDFF).
- 定量超声波方法的概述,包括减弱系数,声速,反射散射,超声波衍生脂肪分数 (UDFF),声结构量化 (ASQ) 和组织散射分布成像 (TSI).
- 讨论儿科特异性考虑:临床指示,患者准备,设备,获取和混因素.
主要成果:
- 核磁共振-PDFF是肝脏脂肪量化的精确生物标志物.
- 定量超声波方法正在成为评估肝硬化症的有效工具.
- 基于超声波的测量可以作为儿童群体中疑似MASLD的有价值的查工具.
结论:
- 无论是MRI-PDFF还是定量超声波技术,都提供了可靠的方法来评估儿童肝硬化症.
- 为了在儿科实践中成功实施,需要定制的策略.
- 这些定量成像生物标志物对于儿童肝病的诊断和管理至关重要.
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