先天性心脏缺陷的严重程度会影响长期的身体发育
Alexandra Kiess1,2, Patricia Bimboese3, Ruth Gausche4,5,6
1Department of Child and Adolescent Medicine, Section of Pediatric Cardiology, University Hospital Jena, Am Klinikum 1, 07747, Jena, Germany. alexandramiriam.kiess@med.uni-jena.de.
Pediatric cardiology
|March 5, 2025
概括
患有先天性心脏缺陷 (CHD) 的儿童经历了生长受影响,更严重的疾病导致身高,体重和头部周长较小. 早期监测这些儿童的成长是及时干预的关键.
科学领域:
- 儿科 儿科 儿科
- 心脏病学 心脏病学
- 发展生物学 发展生物学
背景情况:
- 治疗方面的进步改善了先天性心脏缺陷 (CHD) 的儿童的健康结果.
- 增长是健康发展的关键指标,特别是在患有慢性病如心脏病的儿童中.
研究的目的:
- 评估和比较患有心血管疾病的儿童与健康同龄人的生长参数 (身高,体重,头周长).
- 研究CHD严重程度对生长轨迹的影响.
主要方法:
- 对18591名0-18岁儿童的标准化生长测量 (身高,体重,头周长) 的回顾性纵向分析.
- 来自德国儿科医生网络CrescNet的数据,将心脏病患者与健康对照进行比较.
- 排除患有其他增长改变条件或药物的患者;根据严重程度分类的CHD (轻度,中度,严重).
主要成果:
- 患有心血管疾病的儿童,特别是那些有更严重缺陷的儿童,与健康同龄人以及那些患有较轻微心血管疾病的儿童相比,身高,体重和头部周长都较小.
- 心血管疾病的严重程度显著影响了从出生开始的长期生长参数.
- 在患有唐氏综合征的小组 (T21) 中,心血管疾病的存在,而不是严重程度,与明显较小的测量结果相关.
结论:
- 尽管存活率有所提高,但心血管疾病儿童的生长仍然受到影响,需要密切监测.
- 增长评估是儿童心脏病患者健康发育的重要标志物.
- 早期干预策略应考虑对患有先天性心脏缺陷的儿童进行生长监测.
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