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Updated: May 24, 2025

Evaluation of Exon Inclusion Induced by Splice Switching Antisense Oligonucleotides in SMA Patient Fibroblasts
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在Titin弹性弹区域中对外子使用的反意义介导调节调节了sarcomere功能

Selvi Celik1,2, Ludvig Hyrefelt1, Tomasz Czuba1,2,3,4

  • 1Division of Cardiology, Department of Clinical Sciences, Lund University, BMC D12, Solvegatan 19, Lund SE-221 84, Sweden.

Cardiovascular research
|March 5, 2025
PubMed
概括

自然的反意义转录 (NATs) 调节了Titin (TTN) 拼接. 在心脏细胞中的TTN-AS1-276敲击改变了TTN拼接,改善了瘤细胞的功能和放松,这表明它是心力衰竭的治疗标.

关键词:
没有编码的RNA.瘤瘤的功能功能拼接 拼接 拼接 拼接标题: 一个人的心

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