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Updated: Jun 16, 2026

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries
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一个眼睛基因组表达图书馆用于遗传分区和细胞系丰富分析

Pirro G Hysi1,2,3, Christopher J Hammond1,2

  • 1Academic Ophthalmology, King's College London, London, United Kingdom.

Investigative ophthalmology & visual science
|March 5, 2025
PubMed
概括

这项研究创建了一个眼睛转录组图书馆,将基因表达数据与全基因组关联研究 (GWAS) 联系起来. 本资源识别了参与常见眼睛疾病的特定细胞类型,如折射误差和青光眼.

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Author Spotlight: Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens09:33

Author Spotlight: Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens

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相关概念视频

DNA Microarrays02:34

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...