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Updated: May 24, 2025

Application and Methodology of the Non-destructive 19F Time-domain NMR Technique to Measure the Content in Fluorine-containing Drug Products
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Application and Methodology of the Non-destructive 19F Time-domain NMR Technique to Measure the Content in Fluorine-containing Drug Products

Published on: August 22, 2017

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使用先进的固态NMR检测对制药水合物中联相互作用的的影响

Chaithanya Hareendran1,2, T G Ajithkumar1,2

  • 1Central NMR Facility and Physical/Materials Chemistry Division, CSIR-National Chemical Laboratory, Pune 411008, India.

Molecular pharmaceutics
|March 5, 2025
PubMed
概括

先进的NMR研究表明,在脱水后,regorafenib单酸经历了最小的结构变化. 在这种活性药物成分 (API) 水合物中引入,限制了结,与其类型相比,sorafenib.

关键词:
DQSQQQ 是一个很好的方法.通过气结合,形成了气结合.制药水合物 制药水合物雷戈拉芬尼布的使用情况固态NMR是一种固态NMR.

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