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Updated: May 24, 2025

Examining BCL-2 Family Function with Large Unilamellar Vesicles
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由小分子揭示的BAX和BAK亡活动的不同调节

Kaiming Li1,2, Yu Q Yap1,2, Donia M Moujalled1,2

  • 1Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.

Science advances
|March 5, 2025
PubMed
概括

一个新型分子,WEHI-3773,通过向VDAC2和亲细胞亡蛋白BAK和BAX之间的相互作用来调节细胞亡. 这种药物在某些白血病中促进细胞死亡,提供了一种新的治疗途径.

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