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Updated: Aug 8, 2026

Induction of Experimental Autoimmune Encephalomyelitis in Mice and Evaluation of the Disease-dependent Distribution of Immune Cells in Various Tissues
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Published on: May 8, 2016

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爱斯坦-巴尔病毒感染在多发性硬化症的人性化小鼠模型中促进T细胞失调

Jessica R Allanach1, Naomi M Fettig1, Blair K Hardman1

  • 1Department of Microbiology and Immunology, The University of British Columbia, Vancouver, BC, Canada.

Science advances
|March 5, 2025
PubMed
概括

爱斯坦-巴尔病毒 (EBV) 感染和多发性硬化症 (MS) 有关. 在小鼠模型中,EBV阳性个体,特别是复发性多发性硬化症 (RRMS) 患者,表现出T细胞活性增加,从而恶化神经症状.

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Mouse Models of Cancer Study02:43

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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...