美国大型怀孕队伍的母亲尿液化物水平:ADORE研究的发现
Adrianne K Griebel-Thompson1, Scott Sands1, Lynn Chollet-Hinton2
1Maternal and Infant Nutrition and Development Lab, Department of Dietetics and Nutrition, University of Kansas Medical Center, Kansas City, Kansas, USA.
Environmental health perspectives
|March 5, 2025
概括
美国中西部妇女的孕产妇尿液化物水平超过了怀孕的安全基准. 较高的水平与社区水的化有关,这表明需要进一步进行区域评估.
科学领域:
- 环境健康 环境健康
- 公共卫生 公共卫生
- 毒理学 毒理学 毒理学
背景情况:
- 新兴研究将母体尿液化物 (MUFsg) 与后代智商降低联系起来.
- 之前对美国孕妇MUFsg的研究仅限于加利福尼亚州.
- 需要更多关于美国不同地区的人口水平MUFsg的数据.
研究的目的:
- 在俄俄州和堪萨斯州的一大群孕妇中测量MUFsg.
- 为了比较社区水的化水平与自来水中估计的化物摄入量与MUFsg.之间的关联.
主要方法:
- 从ADORE队列中的孕妇收集了尿液样本和饮食评估.
- 使用化物敏感电极测量MUFsg,并根据特定重力进行调整.
- 社区水的化水平与参与者的住所相匹配,并使用通用线性模型分析了协会.
主要成果:
- 中位数MUFsg为0.9 mg/L,其中87%的参与者超过了建议的怀孕安全基准.
- 较高的MUFsg水平与较高的社区水化水平和自来水消耗相关.
- 水度较高 (≥0.7 mg/L) 的地区的妇女的MUFsg明显高于度较低 (<0.7 mg/L) 的地区的妇女.
结论:
- 美国中西部人口的MUFsg水平超过了怀孕的安全基准.
- 虽然并没有考虑所有化物来源,但MUFsg显示与社区水化有相关性.
- 建议在美国其他地区进行进一步的MUFsg评估,特别是那些水化超过联邦指南的地区.
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