摘要和主要文本报告之间的不一致性在手术干预的试点随机对照试验中很常见:一项方法调查调查
Tyler McKechnie1, Tania Kazi2, Victoria Shi2
1Division of General Surgery, Department of Surgery, McMaster University, Hamilton, ON, Canada; Department of Health Research Methodology, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
American journal of surgery
|March 5, 2025
概括
大多数手术试点和可行性试验显示,摘要和主要文本之间的报告不一致. 改进抽象报道需要作者和期刊的协作努力,以提高科学准确性.
科学领域:
- 医学研究方法学 医学研究方法学
- 手术试验的试验
- 科学报告标准 科学报告标准
背景情况:
- 抽象和主要文本报告之间的不一致性在随机对照试验中很常见.
- 这个问题以前没有在试点和可行性试验中被探索过.
- 本研究研究了手术试点和可行性试验中的抽象主要文本报告的一致性.
研究的目的:
- 评估在手术试点和可行性试验中抽象和主要文本报告中的不一致程度.
- 识别特定类型的报告不一致性.
- 探索试验特征与报告不一致性之间的关联.
主要方法:
- 对2011年和2021年进行了Medline,Embase和CENTRAL数据库的系统搜索.
- 包括的研究是手术干预的试点或可行性随机试验.
- 与主要文本相比,不一致性是由更强烈的结论,遗漏的负面结果,不同的结果或摘要中未说明的陈述来定义的.
主要成果:
- 在包括的72项试验中,69.4%的试验显示了抽象-主要文本报告不一致.
- 具体的不一致性包括:更强烈的结论 (19.4%),遗漏的负面结果 (26.4%),不同的初级结果 (37.5%),和未说明的索赔 (48.6%).
结论:
- 大多数手术试点和可行性试验显示,摘要和主要文本之间存在重大报告不一致.
- 作者和期刊必须实施措施,以提高这些关键试验类型的抽象报道的准确性和一致性.
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