在衰老和阿尔茨海默病早期阶段,用于空间导航的认知运动框架
1Psychology Department, University of Arizona, USA.
概括
空间导航随着年龄和阿尔茨海默病的发展而下降. 新出现的证据表明,这些下降与身体流动性有关,而不仅仅是认知因素.
科学领域:
- 神经科学是一个神经科学.
- 老年学是一门学科.
- 认知科学 认知科学
背景情况:
- 空间导航对于独立至关重要,并且随着阿尔茨海默病等与年龄相关的神经退行性疾病的出现而下降.
- 目前的模型侧重于认知因素,忽视了步态和平衡等身体方面.
- 在神经退行性疾病的早期,导航和移动性都受到影响.
研究的目的:
- 为与年龄相关的空间导航下降提出一个替代模型.
- 突出认知和运动功能在导航中的相互联系.
- 建议空间导航作为衰老的认知运动现象型.
主要方法:
- 审查新出现的证据,将空间导航与功能移动性联系起来.
- 对重叠的感官系统,认知过程和大脑结构的分析.
- 拟议的认知运动模型与传统的认知焦点模型的比较.
主要成果:
- 空间导航和功能移动性共享重叠的神经和认知资源.
- 这些共享系统对健康衰老和病态衰老都很脆弱.
- 神经调节和感官系统的早期缺陷可能会先于海马或脑内皮层的变化.
结论:
- 老龄化和阿尔茨海默病的空间导航下降可能源于综合性认知运动缺陷.
- 将空间导航视为一种认知运动现象型,为与年龄相关的认知功能障碍提供了新的视角.
- 早期发现双重赤字可能会导致新的干预措施.
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