在口腔状细胞癌患者中,电子香烟与可燃香烟相比:系统性审查
Martín Pérez-Leal1, Bouchra El Helou1, Inés Roger1
1Universidad Europea de Valencia, Faculty of Health Sciences, Valencia, Spain.
概括
口腔状细胞癌 (OSCC) 主要与可燃香烟有关,电子烟的相关性较小. 这两种吸烟类型都表现出类似的癌前病变率,通常在舌头上.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 毒理学 毒理学 毒理学
背景情况:
- 口腔状细胞癌 (OSCC) 是与吸烟有关的重大健康问题.
- 电子烟被推广为戒烟,但引起了对潜在的口腔健康风险的担忧.
- 新出现的证据表明,电子烟也可能导致不良健康影响.
研究的目的:
- 确定在OSCC患者中使用可燃和电子烟的流行率.
- 评估与可燃和电子烟吸烟有关的癌前病变的流行情况.
- 描述这些患者群体中OSCC的共同位置和差异化.
主要方法:
- 遵守PRISMA系统审查指南.
- 在PubMed,Web of Science和Scopus数据库中进行全面的文献搜索.
- 利用了针对可燃/电子烟和OSCC的搜索算法.
主要成果:
- 在最初选的400项中,有15项研究符合纳入标准.
- 在OSCC患者中,可燃香烟吸烟的患病率为56.38%,癌前病变为2.50%.
- 在OSCC患者中,电子烟使用率为4.26%,癌前病变为2.20%.
- 舌头和下唇被确定为两种吸烟类型的常见OSCC位置.
结论:
- 可燃香烟仍然是OSCC的主要病因因素.
- 电子烟与OSCC发展的相关性较低,但仍存在.
- 可燃和电子烟都与类似的癌前口腔病变发生率有关,特别是在舌头上.
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