来自一合成的甲基醇载纤维素纳米纤维的结构性质和持续的抗菌活性,通过现场动态微流化合成
Wanwitoo Wanmolee1, Wasawat Kraithong2, Jakkapop Phanthasri2
1Department of Chemical Engineering, Faculty of Engineering, King Mongkut's University of Technology North Bangkok (KMUTNB), Bangkok 10800, Thailand; Center of Eco-Materials and Cleaner Technology, King Mongkut's University of Technology North Bangkok, Bangkok 10800, Thailand.
International journal of biological macromolecules
|March 5, 2025
概括
这项研究开发了一种环保的方法,使用微流体化制造模浸纤维素纳米纤维 (CNFs). 由此产生的CNF显示持续的抗微生物释放和强大的细菌抑制.
科学领域:
- 材料科学 材料科学 材料科学
- 生物技术是生物技术.
- 化学工程是化学工程的重要组成部分.
背景情况:
- 纤维素纳米纤维 (CNF) 具有可调节的物理化学特性.
- 表面修改是提高CNF功能的关键.
- 对于各种CNF应用,抗菌性质是可取的.
研究的目的:
- 开发一种环保的,单阶段的方法,用乙醇浸CNF.
- 优化浸条件,以保持CNF的结构和特性.
- 为了评估含醇的CNF的抗菌疗效和释放特征.
主要方法:
- 单阶段的现场动态高压微流化.
- 探索用于浸的各种乙醇-水比率.
- 使用先进的分析技术进行物理化学表征.
- 密度函数理论 (DFT) 用于吸附分析.
主要成果:
- 在10:90乙醇-水比率 (E10W90) 实现最佳浸.
- 在50小时内,持续释放的甲状腺醇高达27.5%.
- 在3小时内完全抑制*S. aureus*和*E. coli*.
- 据DFT证实,结促进了醇在CNF上的吸附.
结论:
- 建立了一种新的,高能效的方法,用于CNFs的乳浸.
- 浸的CNF表现出长时间和有效的抗微生物活性.
- 这种方法避免了复杂的表面修改,以提高功能.
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