破解黑色素瘤的盔甲:对XPO1和β-catenin进行超分子双重打击,以克服抵抗力

Yinliang Lu1, Ruishan Guo1, Wenfei Song1

  • 1Department of Radiation Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.

PubMed
概括

这项研究开发了XPinβ,这是一种针对黑色素瘤的新型双治疗方法,可以抑制XPO1和β-catenin,克服对XPO1抑制剂的耐药性,并显著抑制瘤生长和转移.

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