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基于试验的经济评估,多组件的积极心理学干预对双相情感障碍的euthymic患者

Anne Kleijburg¹, Frederique Klein², Ben Wijnen³

¹Department of Health Services Research, CAPHRI Care and Public Health Research Institute, Maastricht University, Maastricht, the Netherlands; Centre for Economic Evaluations & Machine Learning, Trimbos Institute, Netherlands Institute of Mental Health and Addiction, Utrecht, the Netherlands.

Journal of affective disorders

|March 5, 2025

概括

对双相情感障碍 (BD) 的积极心理干预 (PPI) 更有效,并且比单独治疗通常的治疗成本更高. 这项研究发现,PPI可能是BD患者在euthymic阶段的成本效益.

科学领域:

心理健康研究心理健康研究
卫生经济学卫生经济学
心理干预心理干预

背景情况:

对双相情感障碍 (BD) 的积极心理学干预 (PPI) 的成本效益仍然没有评估.
这项研究评估了一种多组件PPI的成本效益",生活良好与双相情感障碍",对于euthymic BD患者与通常治疗 (TAU) 相比.

研究的目的:

为了确定"生活得很好与双相情感障碍"PPI与TAU相比的成本效益,用于BD在euthymic阶段的个体.
评估健康结果,包括福利和质量调整寿命 (QALYs),以及相关的医疗保健和生产力成本.

主要方法:

评估了96名在euthymic阶段患有BD的参与者,其中53人被随机分配到干预组.
实用性得分 (EQ-5D-5L),福祉 (MHC-SF),医疗保健成本和生产力损失在基线,6个月和12个月被测量.
增量成本效益比率 (ICUR) 和成本效益比率 (ICER) 估计使用非参数引导和灵敏度分析.

主要成果:

该PPI导致估计的增量成本差异为691欧元和0.04增量QALY,每获得QALY的ICUR为19,669欧元.
在每QALY的支付意愿为50,000欧元时,成本效益的概率为~70%.
增量治疗反应为0.12,ICER为每位额外的响应者5624欧元.

结论:

"双相情感障碍的良好生活"PPI似乎可能对优性BD患者具有成本效益,以额外的成本提供改善的健康结果.
结果支持将这种PPI纳入BD的治疗选择.
需要进一步的研究,但研究结果表明,PPI是TAU对BD管理的宝贵补充.

关键词:

双极性障碍是一种双极性障碍.经济效益性经济效益性优性阶段优性阶段个人恢复个人恢复积极心理学干预是积极心理学干预.幸福是一种幸福.

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