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Updated: Jul 6, 2026

Manufacturing Chimeric Antigen Receptor CAR T Cells for Adoptive Immunotherapy
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[针对复发性/耐药性扩散性大B细胞淋巴瘤的Axicabtagene ciloleucel治疗结果:单一机构的回顾性分析]

Wataru Kitamura1,2, Nobuharu Fujii1,2, Chihiro Kamoi1,2

  • 1Department of Hematology and Oncology, Okayama University Hospital.

[Rinsho ketsueki] The Japanese journal of clinical hematology
|March 5, 2025
PubMed
概括

艾克西卡巴特基因 ciloleucel (axi-cel) 在治疗复发性/耐药性扩散性大B细胞淋巴瘤 (DLBCL) 中显示出高的有效性和安全性. 这项在日本进行的现实研究发现,轴细胞治疗的无进展和整体存活率有前途.

关键词:
艾克西卡巴泰基因 ciloleucelel 的使用情况皮质类固醇是一种皮质类固醇.现实世界的数据数据.复发性/耐药性扩散性大B细胞淋巴瘤

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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...