儿童和青少年牙损伤风险预测模型:系统性审查和元分析
Xijia Wang1,2, Peng Zhang2, Huifei Lu1,2
1Department of Graduate and Scientific Research, Zunyi Medical University Zhuhai Campus, Zhuhai, Guangdong, People's Republic of China.
BMJ open
|March 5, 2025
概括
对儿童的简化牙损伤预测模型显示中度准确性,但具有高偏差风险. 未来的研究必须提高模型质量和验证,以便可靠的临床使用.
科学领域:
- 牙科公共卫生 牙科公共卫生
- 生物统计学 生物统计学
- 流行病学 流行病学
背景情况:
- 牙损仍然是儿童和青少年的全球重大健康问题.
- 准确的预测模型对于早期干预和预防策略至关重要.
- 现有的儿童虫预测模型需要进行系统的评估.
研究的目的:
- 系统地评估已发表的儿童和青少年牙损伤预测模型.
- 评估这些模型的偏差和歧视性性能风险.
主要方法:
- 一个系统的审查和观测研究的元分析.
- 在多个数据库中进行的搜索截至2024年1月.
- 包括研究开发18岁或更年轻人虫风险预测模型的研究.
主要成果:
- 包括11项研究,所有模型都显示出高偏差风险.
- 常见的方法包括后勤回归,随机森林和支向量机器.
- 曲线下的面积 (AUC) 值在0.57到0.91之间,组合模型的AUC值为0.79.
结论:
- 简化儿童虫预测模型的性能中等,但偏差很高.
- 建议遵守预测模型偏差风险评估工具 (PROBAST) 的指导方针.
- 未来的研究应该优先考虑模型质量,严格的设计和外部验证.
相关概念视频
01:15Teeth
282
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
282
01:21Tooth Anatomy
318
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
318