实施基于指导方针的脂质报告和降脂疗法处方率
Anish Adhikari1, Aya Haghamad2, Xueqi Huang3
1Northwell, Cardiovascular Institute, Lenox Hill Hospital, New York, NY (Drs Adhikari, Rubin, Carrero-Tagle and Gianos).
更新的脂质报告准则增加了对需要治疗的患者的降脂疗法 (LLT) 处方. 这一变化改善了对管理胆固醇水平的临床指南的遵守.
科学领域:
- 心脏病学 心脏病学
- 临床信息学 临床信息学
- 公共卫生 公共卫生
背景情况:
- 脂质目标的实现往往是低于最佳的,受患者,提供者和系统因素的影响.
- 有效地管理失脂症是预防动脉样硬化心血管疾病 (ASCVD) 的关键.
研究的目的:
- 为了评估是否更新,基于指南的脂质报告和临床决策支持会影响降脂疗法 (LLT) 处方模式.
- 评估增强脂质测试报告对临床实践中LLT启动率的影响.
主要方法:
- 2019-2021年电子健康记录 (EHR) 数据的回顾性分析.
- 实验室报告前90天内LLT处方的比较,以及基于指导方针的报告变化后的比较.
- 包括成年患者按年龄和心血管风险分层 (LDL-C水平).
主要成果:
- 对于40岁以上的患者,LDL-C≥100 mg/dL的患者,LLT启动率显著增加 (11.6%对16.3%,P<.001).
- 在ASCVD和LDL-C≥70 mg/dL的成年患者中观察到更高的LLT启动率 (25.9%与31.8%,P<.001).
- 更新的报告系统与适合患者的LLT处方率更高有关.
结论:
- 基于指导方针的更新脂质测试报告的实施与LLT启动的增加有关.
- 基于指导方针的报告可以作为一种有效的工具,以改善对脂质管理临床指导方针的实施.
- 通过加强报告来优化脂质管理可能会改善心血管疾病的结果.
更多相关视频
07:29Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein
Published on: October 12, 2017
08:45LDL Cholesterol Uptake Assay Using Live Cell Imaging Analysis with Cell Health Monitoring
Published on: November 17, 2018
相关概念视频
Lipid-Lowering Drugs: Statins and Miscellaneous Agents
Blood Studies for Cardiovascular System III: Serum Lipid Profile
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Lipids: Dietary Sources and Requirements
Cholesterol: Significance and Regulation
Considering cholesterol and...
Dosage Regimen: Fixed Dose
Fixed-dose regimens can be used for various routes of administration, including intravenous (IV) injections and oral medications. For IV administration, a predetermined amount of the drug is...
Overview of Lipid Metabolism
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
