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相关概念视频

Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

226
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
226
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

369
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
369

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相关实验视频

Updated: Dec 26, 2025

Supervised Machine Learning for Semi-Quantification of Extracellular DNA in Glomerulonephritis
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Supervised Machine Learning for Semi-Quantification of Extracellular DNA in Glomerulonephritis

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带有脑膜炎的颗粒状多炎:一个病例报告

Whei Chuern Yeoh1, Cristina Estrach2, Jagdish Nair2

  • 1Department of Rheumatology, Aintree University Hospitals NHS Foundation Trust, Liverpool, UK wchuern53@gmail.com.

Practical neurology
|March 5, 2025
PubMed
概括

带有多炎 (GPA) 的颗粒瘤病可以影响神经系统和肺部. 早期诊断和组合治疗,包括rituximab和avacopan,对于严重GPA病例的缓解至关重要.

科学领域:

  • 神经学 神经学
  • 类风湿病学 类风湿病学
  • 肺部病理学 肺部病理学

背景情况:

  • 带有多叶膜炎 (GPA) 的粒状瘤炎是一种罕见的自身免疫性血管炎.
  • GPA可以呈现出各种神经和系统表现.
  • 神经病变和脑膜炎是不常见但严重的GPA并发症.

研究的目的:

  • 报告一个GPA病例,呈现出复杂的神经和系统性参与.
  • 突出GPA的诊断挑战和治疗策略.
  • 评估新型治疗剂在耐火性GPA中的疗效.

主要方法:

  • 一个33岁的男性患有头痛和神经病的病例介绍.
  • 诊断工作包括MRI,CSF分析,脑膜活检和CT胸部.
  • 使用环胺,皮质类固醇,修复剂和阿瓦科潘的治疗.

主要成果:

  • 通过活检证实了GPA的诊断,其中包括头骨底部质量,脑膜炎,西格结血栓症和肺结节.
  • 最初用环胺和皮质类固醇治疗导致大气泡出血和多重单单尿道炎.
  • 随后的治疗与rituximab和avacopan导致临床改善和缓解.
关键词:
风湿病学 在风湿病学方面.血管炎 (VASCULITIS) 是一种

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Last Updated: Dec 26, 2025

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Published on: June 18, 2020

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结论:

  • 平均成绩要求对各种陈述具有很高的怀疑指数.
  • 与rituximab和avacopan的联合治疗可以在严重或耐火的GPA中有效.
  • 多学科管理对于优化GPA的结果至关重要.