全身冷疗法可以减少人类的炎症反应:基于11项随机对照试验的元分析
Jun He1,2, Xinyu Zhang3, Zhili Ge3
1China Ordnance Industry Group-machine-environment Key Laboratory, Institute for Hygiene of Ordnance Industry, NO.12 Zhangba East Road, Yanta District, Xi'an, 710065, Shaanxi, China. hejun152@126.com.
Scientific reports
|March 5, 2025
概括
全身冷疗法 (WBC) 通过降低IL-1β并增加IL-10水平来减少炎症. 这种疗法对运动员和寻求提高再生能力的肥胖个体具有显著的益处.
科学领域:
- 运动医学 运动医学
- 免疫学 免疫学 免疫学
- 生理学 生理学 生理学
背景情况:
- 全身冷疗法 (WBC) 正因其提高再生能力的潜力而受到关注.
- 需要对WBC的抗炎作用进行全面的总结.
研究的目的:
- 系统地评估WBC对人类炎症反应的影响,使用随机对照试验 (RCT).
主要方法:
- 进行了11个RCT (274名参与者) 的元分析.
- 搜索了PubMed,科学网,Embase和柯克兰图书馆的数据库.
- 使用PEDro尺度评估偏差风险,使用GRADE尺度评估证据确定性.
主要成果:
- 白血球显著降低了血清IL-1β水平 (SMD = -2.08 pg/mL,P < 0.05),特别有利于运动员.
- 白血球显著增加了血清IL-10水平 (SMD = 0.78 pg/mL,P < 0.05),肥胖个体显示出比运动员更大的益处.
结论:
- 通过调节IL-1β和IL-10水平,WBC有效地减少炎症.
- 通过减轻炎症标志物,WBC为运动员和肥胖人士提供治疗潜力.
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