膀出口阻塞的临床预测因素在男性咨询常规泌尿学查
Massimiliano Raffo1,2, Paolo Capogrosso3, Edoardo Pozzi1,2
1Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Via Olgettina 60, 20132, Milan, Italy.
International urology and nephrology
|March 5, 2025
概括
40岁以上的男性出现下尿路症状 (LUTS),应进行膀出口阻塞 (BOO) 查. 前列腺体积 (PV) 和国际前列腺症状评分 (IPSS) 可以帮助预测BOO风险.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 男人的健康 男人的健康
- 诊断预测器的诊断预测
背景情况:
- 低尿路症状 (LUTS) 在男性中很常见,通常与膀出口阻塞 (BOO) 相关.
- 这些症状经常被低估,使早期诊断和干预复杂化.
- 确定BOO的预测因子对于受影响男性的及时管理至关重要.
研究的目的:
- 在患者初次泌尿外科诊所期间确定膀出口阻塞 (BOO) 的预测因素.
- 评估预测BOO的关键参数的诊断准确性.
- 建立前列腺体积 (PV) 的门值,表明BOO风险.
主要方法:
- 分析了1045名40岁以上的男性的数据,不包括前列腺癌或之前接受过BOO治疗的人.
- 患者完成了国际前列腺症状评分 (IPSS),并接受前列腺特异性抗原 (PSA) 测试,前列腺体积 (PV) 的跨直肠超声波和尿液流量测试.
- 后勤回归和接收器运行特征 (ROC) 曲线分析被用于识别预测因素和评估诊断准确性.
主要成果:
- 前列腺体积 (PV) 和国际前列腺症状评分 (IPSS) 在调整年龄后都与膀出口阻塞 (BOO) 有显著的关联.
- PV显示预测精度 (AUC) 为0.69,而IPSS的AUC为0.63.
- 前列腺体积 (PV) 为43毫升被确定为切断点,60岁的男性和PV≥43毫升具有84%的BOO风险.
结论:
- 由于患病率很高,建议40岁以上的男性进行与BOO相关的LUTS查.
- 前列腺体积 (PV) 和IPSS是用户友好的参数,可以有效地指导BOO的进一步调查.
- 早期识别BOO预测因素可以导致及时诊断和管理,改善患者的治疗结果.
相关概念视频
01:20Disorders of the Male Reproductive System
289
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
289
01:20Disorders of the Urinary System
208
The urinary system is responsible for eliminating waste and excess fluids from the body. However, disorders of the urinary system can arise due to various reasons like infections, stress, age, congenital abnormalities, and lifestyle.
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
208
01:23Urinary Bladder
307
The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
307