Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

High-throughput combinatorial screening of antiplatelet drugs for personalized medicine.

Microsystems & nanoengineering·2025
Same author

Leukocyte telomere length and risk of heart failure with preserved ejection fraction in high-risk Chinese patients with hypertension under 65 years.

GeroScience·2025
Same author

Mitochondrial Amount Determines Doxorubicin-Induced Cardiotoxicity in Cardiomyocytes.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2025
Same author

Protease activated receptor 2 deficiency retards progression of abdominal aortic aneurysms by modulating phenotypic transformation of vascular smooth muscle cells via ERK signaling.

Experimental cell research·2024
Same author

Cystathionine γ-lyase inhibits mitochondrial oxidative stress by releasing H<sub>2</sub>S nearby through the AKT/NRF2 signaling pathway.

Frontiers in pharmacology·2024
Same author

Targeting Rab7-Rilp Mediated Microlipophagy Alleviates Lipid Toxicity in Diabetic Cardiomyopathy.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2024

相关实验视频

Updated: May 24, 2025

Microfluidics in Assessing Platelet Function
06:47

Microfluidics in Assessing Platelet Function

Published on: November 8, 2024

738

星云板:一个滴滴微流体平台,用于分析血小板聚合.

Zheyi Jiang1, Meng Wei1, Jiawei Zhu2

  • 1Department of Cardiology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China.

Journal of nanobiotechnology
|March 5, 2025
PubMed
概括

NebulaPlate是一种新的微滴子方法,用于使用最小的血液样本评估血小板活动. 这种技术增强了对抗血小板治疗心血管疾病的评估.

关键词:
微小的小滴是什么意思微流体芯片是一个微流体.在P-selectin中进行选择.血小板聚合是血小板的聚合.血小板功能 血小板功能

更多相关视频

Platelet Adhesion and Aggregation Under Flow using Microfluidic Flow Cells
10:10

Platelet Adhesion and Aggregation Under Flow using Microfluidic Flow Cells

Published on: October 27, 2009

18.1K
A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time
09:38

A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time

Published on: February 14, 2017

13.7K

相关实验视频

Last Updated: May 24, 2025

Microfluidics in Assessing Platelet Function
06:47

Microfluidics in Assessing Platelet Function

Published on: November 8, 2024

738
Platelet Adhesion and Aggregation Under Flow using Microfluidic Flow Cells
10:10

Platelet Adhesion and Aggregation Under Flow using Microfluidic Flow Cells

Published on: October 27, 2009

18.1K
A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time
09:38

A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time

Published on: February 14, 2017

13.7K

科学领域:

  • 生物医学工程 生物医学工程
  • 血液学 血液学 血液学
  • 心血管研究研究心血管研究

背景情况:

  • 准确的血小板活动评估对于心血管疾病管理至关重要.
  • 目前的方法需要大量的血液,缺乏高通量分析.
  • 对抗血小板剂的治疗耐药性构成了重大的临床挑战.

研究的目的:

  • 开发一种小型化,高通量的血小板功能检测方法.
  • 克服传统血小板活动评估技术的局限性.
  • 为了能够对抗血小板药物的有效性进行可靠的评估.

主要方法:

  • 开发了NebulaPlate,一种基于微滴的血小板功能检测系统.
  • 使用 picoliter 微滴,用于样品与药物合并和基于成像的分析.
  • 在微滴中评估了血小板聚合和P-选择因表达.

主要成果:

  • 每次测试,NebulaPlate只需要0.3毫升的全血,减少了10倍.
  • 实验验证证证实了用抗血小板药物进行聚合分析的可行性.
  • 证明了血小板功能试验的有效性和可重复性.

结论:

  • NebulaPlate提供了一种小型化和强大的血小板活动评估方法.
  • 这种方法为抗血小板疗法和个性化医学提供了新的前景.
  • 介绍了动脉血栓性疾病的研究和临床实践的进展.