博尔尼亚蝙蝠的肠道微生物群社区概况,具有不同的养协会
Muhd Amsyari Morni1,2, Julius William-Dee3, Emy Ritta Jinggong3
1Faculty of Resource Science and Technology, Universiti Malaysia Sarawak, Sarawak, 94300, Kota Samarahan, Malaysia. mmamsyari@unimas.my.
Animal microbiome
|March 5, 2025
概括
这项研究揭示了婆罗洲蝙蝠的肠道微生物组,发现了像Bacillota和Pseudomonadota这样的各种细菌. 乳酸菌通过抑制病原性细菌来表现出前生物的潜力.
科学领域:
- 微生物学 微生物学
- 哺乳动物学 哺乳动物学
- 基因组学就是基因组学.
背景情况:
- 蝙蝠表现出多样化的饮食,影响其肠道微生物组合.
- 了解蝙蝠肠微生物组对于生态和进化研究至关重要.
- 东南亚,特别是婆罗洲,拥有丰富的蝙蝠动物群,但微生物组数据有限.
研究的目的:
- 提供 Bornean蝙蝠肠微生物组的开创性下一代测序 (NGS) 元编码数据.
- 研究蝙蝠饮食和肠道微生物群落之间的相关性.
- 描述蝙蝠肠微生物组内的功能性作用和相互作用.
主要方法:
- 利用基于纳米孔的高通量16SrRNA基因测序.
- 分析了昆虫食和植物食蝙蝠的肠道微生物组合.
- 进行了肠道细菌功能组的比较分析和相关联网络分析.
主要成果:
- 在食昆虫和植物的蝙蝠中鉴定了Bacillota,Pseudomonadota和Campylobacterota.
- 在这两种饮食组中都没有发现主导性细菌种群.
- 在八个已确定的细菌群体中,发酵是占主导地位的功能组.
- 证明了乳酸菌和致病细菌 (沙门氏菌,耶尔西尼亚菌) 之间的负相关性,表明了益生菌性质.
结论:
- 这项研究扩大了对蝙蝠肠微生物的理解,特别是在婆罗洲.
- 突出了乳杆菌在蝙蝠肠生态系统中的潜在益生菌作用.
- 为未来关于蝙蝠微生物组相互作用和饮食的研究提供基础的NGS数据.
相关概念视频
Methods to Assess Microbial Communities
Microbial communities, comprising bacteria, archaea, and eukaryotic microorganisms, inhabit diverse ecosystems and play crucial roles in environmental and biological processes. Their diversity is defined by three main parameters: species richness (the number of distinct species), species abundance (the relative quantity of each species), and species evenness (how uniformly individual species are distributed in various locations). These factors together shape the structure and ecological balance...
Development of Human Microbiota
The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from the skin...
The Oral Microbiota
The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...
Microbiota of the Respiratory Tract
The human respiratory tract, comprising the upper and lower segments, serves as a critical interface with the external environment. The upper respiratory tract (URT)—including the nostrils, sinuses, pharynx, and oropharynx—is heavily colonized by microbes, while the lower respiratory tract (LRT), composed of the larynx, trachea, bronchi, and lungs, was long thought to be sterile. However, recent molecular studies have revealed that the lungs are not devoid of microbes but act more like...
Microbiota of the Large Intestine
The large intestine hosts the most densely populated microbial ecosystem in the human body. This complex community primarily consists of anaerobic bacteria, with Bacillota (formerly Firmicutes) and Bacteroidota (formerly Bacteroidetes) as the predominant groups. The distribution of these microbes varies along different sections of the large intestine, influenced by local environmental factors such as oxygen availability and nutrient composition.The cecum, located at the beginning of the large...


