SARC-F问卷及其对住院年轻人死亡风险的预测价值:一项回顾性研究
Yuria Ishida1,2, Keisuke Maeda2,3,4, Akio Shimizu2,5
1Department of Nutrition, Aichi Medical University Hospital, Nagakute, Japan.
概括
肉症是一种肌肉损失状况,可以影响年轻成年人. 年轻患者的SARC-F评分为1或以上显著预测死亡率,表明需要早期干预.
科学领域:
- 老年学是指老年学的学科.
- 临床医学 临床医学
- 公共卫生 公共卫生
背景情况:
- 标志着骨肌肉质量和力量的逐渐丧失的萨尔科佩尼亚,可以影响成年人一生中的个人.
- 在评估年轻成年人群中萨尔科佩尼亚风险方面,SARC-F问卷的有用性仍未得到充分研究.
研究的目的:
- 评估SARC-F问卷在预测65岁以下成年人死亡率方面的有效性.
- 确定SARC-F得分与年轻成年人队列中的死亡风险之间的关联.
主要方法:
- 2019年4月至2021年3月期间,12743名年龄在18-64岁之间的患者被录取到大学医院的医疗记录的回顾性分析.
- 在入院时记录的SARC-F得分被分析为它们与死亡率的关联,使用ROC曲线分析和Cox比例危险模型.
主要成果:
- SARC-F评分显示出对死亡率的显著预测价值,ROC曲线下的面积为0.721 (P < 0.001).
- 为了预测死亡率,确定了≥1的最佳SARC-F截止分数.
- 在所有研究年龄组中,SARC-F评分≥1显著与死亡风险比率的增加有关 (范围从3.77到9.47).
结论:
- 年轻成年人SARC-F得分升高与死亡风险增加有显著联系.
- 实施早期识别策略和对SARC-F分数≥1的个体进行干预,可能有助于减少年轻人群中与肉类相关的风险.
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